Hormonal Interactions at the Molecular Level. A Study of Oxytocin and Vasopressin Binding to Bovine Neurophysins

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Interactions of oxytocin and vasopressin with bovine neurophysins I and II. Effects of hormone binding on the protein quaternary structure: a simple model.

The effects of hormone binding on the reversible monomer in equilibrium dimer equilibrium of bovine neurophysins I or II in solution have been studied by sedimentation equilibrium measurements performed in conjunction with equilibrium dialysis experiments. Under normal solution conditions saturating amounts of oxytocin displace the neurophysin dimerization equilibrium toward the associated form...

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ژورنال

عنوان ژورنال: European Journal of Biochemistry

سال: 1973

ISSN: 0014-2956,1432-1033

DOI: 10.1111/j.1432-1033.1973.tb02598.x